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The most common dosage range is between six and nine grams per day, though larger athletes with more muscle mass may want to veer towards the high end of the dosage range.
The most recent meta-analysis of creatine monohydrate studies showed that supplementation with 1 g/day resulted in improvements in strength, power, and body mass, but that supplementation without creatine in the supplement group led to a significantly greater decrease in strength performance.
It has long been known that muscle creatine uptake is greatly diminished by long-term ingestion of creatine monohydrate. This has been called creatine phosphate depletion.
This is also reflected in the fact that athletes with high muscle mass often do not benefit from the optimal dosage of creatine, particularly in a supplementation phase as creatine is quickly metabolized, and the body will therefore have lost all of its stores of the essential amino acid and will have to create its own at the outset.
However, the most common recommendation from sports scientists is a relatively conservative dose based on the body’s ability to re-absorb creatine monohydrate. This is because creatine phosphate must be utilized by the mitochondria to survive, but the body only has relatively limited ability to do so.
To accommodate for this and to prevent creatine phosphate depletion during training, supplementing only with a small amount with a specific dose is usually recommended.
The latest recommendation from scientists is to use 5 g/day of creatine monohydrate for a week during a training camp. However, this dosage is relatively uncommon as athletes often ingest creatine monohydrate in the morning and go into the gym as normal.
The recommended dosage for a period of a week during a training camp on creatine has been given as 150 mg of creatine monohydrate (or 5 g). It has been suggested that this is a very safe dosage, but that the longer it is taken, the less potent it becomes.
Even in athletes who take the recommended dose, they may become significantly less effective at maintaining maximum strength output once their levels reach lower levels.
Furthermore, in those athletes who take this dosage with no other creatine preparation, which is common, creatine-mediated depletion in the mitochondria will be less pronounced.
Although the research currently shows that creatine monohydrate supplementation results in greater gains in strength and body composition relative to other forms of creatine, athletes should not attempt to take a dosage higher than this.
Athletes who are taking the recommended dose are still advised taking a supplement that contains a similar amount of creatine—usually 5 grams or more.
However, the use of high doses of creatine monohydrate results in a significant increase in muscle creatine uptake; this is why athletes should be advised to
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